sábado, 5 de julio de 2014

ATSDR – Priority List of Hazardous Substances

ATSDR – Priority List of Hazardous Substances



The Priority List of Hazardous Substances
That Will Be the Subject of Toxicological Profiles



What is the Substance Priority List (SPL)?



The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) section 104 (i), as amended by the Superfund Amendments and Reauthorization Act (SARA), requires ATSDR and the EPA to prepare a list, in order of priority, of substances that are most commonly found at facilities on the National Priorities List (NPL) and which are determined to pose the most significant potential threat to human health due to their known or suspected toxicity and potential for human exposure at these NPL sites. CERCLA also requires this list to be revised periodically to reflect additional information on hazardous substances.
This substance priority list is revised and published on a 2-year basis, with a yearly informal review and revision. (No list was published in 2009 while ATSDR transitioned to a new agency science database.) Each substance on the list is a candidate to become the subject of a toxicological profile prepared by ATSDR. The listing algorithm prioritizes substances based on frequency of occurrence at NPL sites, toxicity, and potential for human exposure to the substances found at NPL sites.
It should be noted that this priority list is not a list of "most toxic" substances, but rather a prioritization of substances based on a combination of their frequency, toxicity, and potential for human exposure at NPL sites.
Thus, it is possible for substances with low toxicity but high NPL frequency of occurrence and exposure to be on this priority list. The objective of this priority list is to rank substances across all NPL hazardous waste sites to provide guidance in selecting which substances will be the subject of toxicological profiles prepared by ATSDR.

Where can I find more information on the Substance Priority List?



There is a Support Document Adobe PDF file to the Priority List of Hazardous Substances that describes in detail how the list is developed. There is also a Detailed Data Table Adobe PDF file showing the breakdown of the total scores for each substance on the priority list. These documents and other supporting information are available on the Substance Priority List Resource Page.

The ATSDR 2013 Substance Priority List

2013
RANK
SUBSTANCE NAMETOTAL 
POINTS
2011
RANK
CAS RN
1ARSENIC1670.41007440-38-2
2LEAD1529.22007439-92-1
3MERCURY1458.63007439-97-6
4VINYL CHLORIDE1359.84000075-01-4
5POLYCHLORINATED BIPHENYLS1343.55001336-36-3
6BENZENE1328.56000071-43-2
7CADMIUM1318.77007440-43-9
8BENZO(A)PYRENE1304.78000050-32-8
9POLYCYCLIC AROMATIC HYDROCARBONS1279.79130498-29-2
10BENZO(B)FLUORANTHENE1251.210000205-99-2
11CHLOROFORM1203.511000067-66-3
12AROCLOR 12601190.312011096-82-5
13DDT, P,P'-1181.513000050-29-3
14AROCLOR 12541171.214011097-69-1
15DIBENZO(A,H)ANTHRACENE1155.415000053-70-3
16TRICHLOROETHYLENE1151.416000079-01-6
17CHROMIUM, HEXAVALENT1146.917018540-29-9
18DIELDRIN1142.518000060-57-1
19PHOSPHORUS, WHITE1141.419007723-14-0
20HEXACHLOROBUTADIENE1128.220000087-68-3
21DDE, P,P'-1126.221000072-55-9
22CHLORDANE1125.922000057-74-9
23COAL TAR CREOSOTE1124.523008001-58-9
24AROCLOR 12421124.324053469-21-9
25ALDRIN1114.625000309-00-2
26DDD, P,P'-1113.326000072-54-8
27AROCLOR 12481103.827012672-29-6
28HEPTACHLOR1100.728000076-44-8
29AROCLOR1099.429012767-79-2
30BENZIDINE1090.530000092-87-5
31ACROLEIN1088.431000107-02-8
32TOXAPHENE1087.432008001-35-2
33TETRACHLOROETHYLENE1075.733000127-18-4
34YHEXACHLOROCYCLOHEXANE, GAMMA-1074.934000058-89-9
35CYANIDE1070.235000057-12-5
36HEXACHLOROCYCLOHEXANE, BETA-1053.536000319-85-7
37DISULFOTON1047.138000298-04-4
38BENZO(A)ANTHRACENE1046.037000056-55-3
391,2-DIBROMOETHANE1041.739000106-93-4
40ENDRIN1037.740000072-20-8
41DIAZINON1036.641000333-41-5
42HEXACHLOROCYCLOHEXANE, DELTA-1034.842000319-86-8
43BERYLLIUM1031.043007440-41-7
44ENDOSULFAN1027.744000115-29-7
45AROCLOR 12211027.045011104-28-2
461,2-DIBROMO-3-CHLOROPROPANE1025.746000096-12-8
47HEPTACHLOR EPOXIDE1020.947001024-57-3
48ENDOSULFAN, ALPHA1018.048000959-98-8
49CIS-CHLORDANE1015.649005103-71-9
50CARBON TETRACHLORIDE1012.650000056-23-5
51COBALT1011.752007440-48-4
52AROCLOR 10161011.551012674-11-2
53DDT, O,P'-1007.854000789-02-6
54PENTACHLOROPHENOL1007.653000087-86-5
55METHOXYCHLOR1005.955000072-43-5
56ENDOSULFAN SULFATE1003.456001031-07-8
57NICKEL996.257007440-02-0
58DI-N-BUTYL PHTHALATE994.958000084-74-2
59ENDRIN KETONE991.659053494-70-5
60DIBROMOCHLOROPROPANE982.960067708-83-2
61BENZO(K)FLUORANTHENE971.361000207-08-9
62TRANS-CHLORDANE967.863005103-74-2
63ENDOSULFAN, BETA967.264033213-65-9
64XYLENES, TOTAL965.362001330-20-7
65CHLORPYRIFOS963.865002921-88-2
66CHROMIUM(VI) TRIOXIDE960.066001333-82-0
67AROCLOR 1232957.967011141-16-5
68ENDRIN ALDEHYDE957.468007421-93-4
69METHANE952.869000074-82-8
703,3'-DICHLOROBENZIDINE940.472000091-94-1
712-HEXANONE940.370000591-78-6
722,3,7,8-TETRACHLORODIBENZO-P-DIOXIN939.971001746-01-6
73BENZOFLUORANTHENE935.673056832-73-6
74TOLUENE918.874000108-88-3
75ZINC915.575007440-66-6
76PENTACHLOROBENZENE906.877000608-93-5
77DI(2-ETHYLHEXYL)PHTHALATE905.276000117-81-7
78CHROMIUM896.478007440-47-3
79AROCLOR 1240888.379071328-89-7
80NAPHTHALENE878.080000091-20-3
812,4,6-TRINITROTOLUENE877.382000118-96-7
821,1-DICHLOROETHENE876.681000075-35-4
83BROMODICHLOROETHANE866.285000683-53-4
842,4,6-TRICHLOROPHENOL866.083000088-06-2
85BIS(2-CHLOROETHYL) ETHER865.984000111-44-4
86DDD, O,P'-865.687000053-19-0
87HYDRAZINE860.888000302-01-2
88METHYLENE CHLORIDE860.886000075-09-2
892,4-DINITROPHENOL858.189000051-28-5
904,4'-METHYLENEBIS(2-CHLOROANILINE)857.390000101-14-4
911,2-DICHLOROETHANE853.391000107-06-2
92THIOCYANATE845.892000302-04-5
93HEXACHLOROBENZENE843.693000118-74-1
94ASBESTOS840.994001332-21-4
95RADIUM-226832.995013982-63-3
96RDX (Cyclonite)831.996000121-82-4
97URANIUM831.497007440-61-1
982,4-DINITROTOLUENE830.898000121-14-2
99ETHION829.999000563-12-2
100RADIUM827.3100007440-14-4
1014,6-DINITRO-O-CRESOL827.0101000534-52-1
102THORIUM824.0102007440-29-1
103DIMETHYLARSINIC ACID821.1103000075-60-5
104CHLORINE820.3104007782-50-5
1051,3,5-TRINITROBENZENE818.5106000099-35-4
106RADON818.4105010043-92-2
107HEXACHLOROCYCLOHEXANE, ALPHA-816.7107000319-84-6
108RADIUM-228815.1108015262-20-1
109THORIUM-230813.6109014269-63-7
110URANIUM-235812.0111015117-96-1
111THORIUM-228810.2113014274-82-9
112URANIUM-234809.5112013966-29-5
113RADON-222809.2114014859-67-7
1141,1,1-TRICHLOROETHANE808.4110000071-55-6
115COAL TARS808.1115008007-45-2
116METHYLMERCURY807.2120022967-92-6
117N-NITROSODI-N-PROPYLAMINE807.2118000621-64-7
118COPPER806.9125007440-50-8
119CHRYSOTILE ASBESTOS806.1119012001-29-5
120PLUTONIUM-239805.9120015117-48-3
121POLONIUM-210805.5122013981-52-7
122PLUTONIUM-238805.2123013981-16-3
123LEAD-210805.1124014255-04-0
124CHLOROBENZENE804.3117000108-90-7
125AMOSITE ASBESTOS804.2127012172-73-5
125PLUTONIUM804.2127007440-07-5
125STRONTIUM-90804.2127010098-97-2
128RADON-220804.2130022481-48-7
129AMERICIUM-241803.8131086954-36-1
130ETHYLBENZENE803.5116000100-41-4
131BARIUM802.8126007440-39-3
132AZINPHOS-METHYL802.5134000086-50-0
133CHLORDECONE802.1135000143-50-0
134NEPTUNIUM-237801.9136013994-20-2
135HYDROGEN CYANIDE801.6137000074-90-8
136PLUTONIUM-240801.4138014119-33-6
1371,2,3-Trichlorobenzene800.1139000087-61-6
138FLUORANTHENE800.0133000206-44-0
139MANGANESE798.8140007439-96-5
140S,S,S-TRIBUTYL PHOSPHOROTRITHIOATE797.5141000078-48-8
141CHRYSENE791.8142000218-01-9
1422,4,5-TRICHLOROPHENOL790.2143000095-95-4
143POLYBROMINATED BIPHENYLS784.2144067774-32-7
144DICOFOL783.7145000115-32-2
145SELENIUM776.4146007782-49-2
1461,1,2,2-TETRACHLOROETHANE775.8147000079-34-5
147HEPTACHLORODIBENZO-P-DIOXIN773.4148037871-00-4
148PARATHION773.3149000056-38-2
149HEXACHLOROCYCLOHEXANE, TECHNICAL GRADE772.9150000608-73-1
150TRICHLOROFLUOROETHANE772.3151027154-33-2
151BROMINE770.0152007726-95-6
152AROCLOR 1268763.8New011100-14-4
1531,3-BUTADIENE760.9155000106-99-0
154HEPTACHLORODIBENZOFURAN755.2153038998-75-3
155TRIFLURALIN754.2154001582-09-8
1561,2,3,4,6,7,8,9-OCTACHLORODIBENZOFURAN742.6156039001-02-0
157AMMONIA741.2157007664-41-7
1582-METHYLNAPHTHALENE726.8158000091-57-6
1591,4-DICHLOROBENZENE723.4159000106-46-7
1602,3,4,7,8-PENTACHLORODIBENZOFURAN723.4161057117-31-4
1611,1-DICHLOROETHANE722.5160000075-34-3
162NALED720.4162000300-76-5
1631,1,2-TRICHLOROETHANE719.5165000079-00-5
164HEXACHLOROCYCLOPENTADIENE717.9163000077-47-4
1651,2-DIPHENYLHYDRAZINE717.6164000122-66-7
166PHORATE715.0166000298-02-2
167TRICHLOROETHANE712.3167025323-89-1
168ACENAPHTHENE710.2168000083-32-9
169TETRACHLOROBIPHENYL709.1169026914-33-0
170OXYCHLORDANE705.4170027304-13-8
171PALLADIUM705.3171007440-05-3
172CRESOL, PARA-703.2172000106-44-5
173GAMMA-CHLORDENE701.9174056641-38-4
174INDENO(1,2,3-CD)PYRENE701.8173000193-39-5
175TETRACHLOROPHENOL696.9176025167-83-3
1761,2-DICHLOROBENZENE696.6175000095-50-1
1771,2-DICHLOROETHENE, TRANS-692.3177000156-60-5
178CHLOROETHANE687.2178000075-00-3
179ALUMINUM686.6181007429-90-5
180PHENOL686.1179000108-95-2
181P-XYLENE685.9180000106-42-3
182CARBON MONOXIDE682.2183000630-08-0
183CARBON DISULFIDE681.8182000075-15-0
1842,4-DIMETHYLPHENOL679.2184000105-67-9
185DIBENZOFURAN675.8185000132-64-9
186ACETONE673.1186000067-64-1
187HEXACHLOROETHANE669.2187000067-72-1
188Butyl methyl phthalate667.3188034006-76-3
189CHLOROMETHANE665.0189000074-87-3
190HEXACHLORODIBENZOFURAN659.7190055684-94-1
191BUTYL BENZYL PHTHALATE657.6191000085-68-7
192HYDROGEN SULFIDE656.2192007783-06-4
193DICHLORVOS655.3193000062-73-7
194DIBENZOFURANS, CHLORINATED652.8195042934-53-2
195CRESOL, ORTHO-652.4194000095-48-7
196HEXACHLORODIBENZO-P-DIOXIN651.3196034465-46-8
197VANADIUM649.8197007440-62-2
198N-NITROSODIMETHYLAMINE648.2198000062-75-9
1991,2,4-TRICHLOROBENZENE646.4199000120-82-1
200ETHOPROP643.5200013194-48-4
201TETRACHLORODIBENZO-P-DIOXIN641.0201041903-57-5
202BROMOFORM634.3202000075-25-2
203PENTACHLORODIBENZOFURAN631.3203030402-15-4
2041,3-DICHLOROBENZENE627.7204000541-73-1
205PENTACHLORODIBENZO-P-DIOXIN625.4205036088-22-9
206N-NITROSODIPHENYLAMINE624.7206000086-30-6
2072,3,7,8-TETRACHLORODIBENZOFURAN618.7207051207-31-9
2082,4-DICHLOROPHENOL618.0208000120-83-2
2092,3-DIMETHYLNAPHTHALENE617.5209000581-40-8
2101,4-DIOXANE614.8210000123-91-1
211FLUORINE613.2211007782-41-4
212CESIUM-137609.9214010045-97-3
212Chromic Acid609.9214007738-94-5
214NITRITE608.9216014797-65-0
2152-BUTANONE608.3212000078-93-3
2161,2-DICHLOROETHYLENE608.0213000540-59-0
217POTASSIUM-40607.5218013966-00-2
218DINITROTOLUENE607.2219025321-14-6
219SILVER605.4217007440-22-4
220COAL TAR PITCH605.2221065996-93-2
221NITRATE605.1220014797-55-8
222THORIUM-227604.9222015623-47-9
223ARSENIC ACID604.3223007778-39-4
224FORMALDEHYDE604.2241000050-00-0
225ARSENIC TRIOXIDE603.8224001327-53-3
226BENZOPYRENE603.4225073467-76-2
227CHLORDANE, TECHNICAL602.5226012789-03-6
228STROBANE602.5227008001-50-1
2294-AMINOBIPHENYL602.4228000092-67-1
229PYRETHRUM602.4228008003-34-7
231ARSINE602.4230007784-42-1
231DIMETHOATE602.4230000060-51-5
233CARBOPHENOTHION601.9233000786-19-6
234ALPHA-CHLORDENE601.4234056534-02-2
234IODINE-131601.4234010043-66-0
234MERCURIC CHLORIDE601.4234007487-94-7
234SODIUM ARSENITE601.4234007784-46-5
234URANIUM-233601.4234013968-55-3
239ANTIMONY600.7232007440-36-0
240DIBROMOCHLOROMETHANE599.5239000124-48-1
241CRESOLS596.7240001319-77-3
242DICHLOROBENZENE594.9242025321-22-6
2432,4-D ACID594.3243000094-75-7
2442-CHLOROPHENOL590.6244000095-57-8
245BUTYLATE589.8245002008-41-5
246PHENANTHRENE585.2246000085-01-8
247DIMETHYL FORMAMIDE585.2247000068-12-2
2484-NITROPHENOL579.4248000100-02-7
249DIURON578.7249000330-54-1
250TETRACHLOROETHANE576.4250025322-20-7
251DICHLOROETHANE567.4251001300-21-6
252ETHYL ETHER564.9252000060-29-7
253DIMETHYLANILINE561.7254000121-69-7
254PYRENE561.3253000129-00-0
2551,3-DICHLOROPROPENE, CIS-560.5255010061-01-5
2561,2,3,4,6,7,8-HEPTACHLORODIBENZO-P-DIOXIN558.6256035822-46-9
257PHOSPHINE555.2257007803-51-2
258TRICHLOROBENZENE554.9258012002-48-1
2592,6-DINITROTOLUENE554.0259000606-20-2
260FLUORIDE ION549.0260016984-48-8
2611,2,3,4,6,7,8-HEPTACHLORODIBENZOFURAN548.5261067562-39-4
262PENTAERYTHRITOL TETRANITRATE548.1262000078-11-5
2631,3-DICHLOROPROPENE, TRANS-547.6263010061-02-6
264ACRYLONITRILE543.0264000107-13-1
265BIS(2-ETHYLHEXYL)ADIPATE542.2265000103-23-1
266CARBAZOLE538.7266000086-74-8
267METOLACHLOR538.1267051218-45-2
2682-CHLOROANILINE537.9268000095-51-2
2691,2,3-TRICHLOROPROPANE535.9269000096-18-4
270CARBARYL535.4270000063-25-2
2711,2-DICHLOROETHENE, CIS-534.5271000156-59-2
272STYRENE528.1273000100-42-5
273METHYL ISOBUTYL KETONE527.6272000108-10-1
274THALLIUM524.7274007440-28-0
2751,2,3,7,8,9-HEXACHLORODIBENZOFURAN524.0275072918-21-9
Substances were assigned the same rank when two (or more) substances received equivalent total point scores.
CAS #= Chemical Abstracts Service Registry Number

Contact Information

Further information can be obtained by contacting the ATSDR Information Center at:
Agency for Toxic Substances and Disease Registry 
Division of Toxicology and Human Health Sciences
1600 Clifton Road NE, Mailstop F-57
Atlanta, GA 30333 
Phone: 1-800-CDC-INFO 888-232-6348 (TTY) 
Email: Contact CDC-INFO

No hay comentarios:

Publicar un comentario