lunes, 1 de septiembre de 2014

Hereditary cancer syndromes with high risk of e... [J Surg Oncol. 2014] - PubMed - NCBI

Hereditary cancer syndromes with high risk of e... [J Surg Oncol. 2014] - PubMed - NCBI

 2014 Aug 20. doi: 10.1002/jso.23743. [Epub ahead of print]

Hereditary cancer syndromes with high risk of endometrial and ovarian cancer: Surgical options for personalized care.

Abstract

Cancer genomics has increased our recognition of specific hereditary cancer mutations. Hereditary breast and ovarian cancer (HBOC) syndrome and Lynch syndrome are two such entities in which women carrying specific mutations may be at high risk for developing breast, ovarian, and/or endometrial cancers. Risk reducing surgery such as prophylactic mastectomy, oophorectomy, and/or hysterectomy may allow women to decrease these risks after completing childbearing. Background, indications, and consequences of these procedures are reviewed. J. Surg. Oncol. © 2014 Wiley Periodicals, Inc.
© 2014 Wiley Periodicals, Inc.

KEYWORDS:

BRCA; hereditary cancer; lynch

PMID:
 
25139656
 
[PubMed - as supplied by publisher]

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