Genetic Testing Fact Sheet - National Cancer Institute

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Genetic Testing Fact Sheet - National Cancer Institute

Genetic Testing for Hereditary Cancer Syndromes

Key Points

• Genetic mutations play a role in the development of all cancers. Most of these mutations occur during a person’s lifetime, but some mutations, including those that are associated with hereditary cancer syndromes, can be inherited from a person’s parents.
• Inherited mutations play a major role in the development of about 5 to 10 percent of all cancers.
• The genetic mutations associated with more than 50 hereditary cancer syndromes have been identified, and genetic tests can help tell whether a person from a family with such a syndrome has one of these mutations.
• A genetic counselor, doctor, or other health care professional trained in genetics can help an individual or family understand genetic test results.