Hemophilia: Recent Insights - April 14, 2015

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Hemophilia

Hemophilia: Recent Insights - April 14, 2015

CDC Info

• Do you have hemophilia and an inhibitor?
• CDC information on hemophilia
• Many people with hemophilia will develop an inhibitor
• Hemophilia and maintaining a healthy weight
• The safety of blood products is important for people with hemophilia

CDC information: Do you have hemophilia and an inhibitor?

The current status of prophylactic replacement therapy in children and adults with haemophilia.
Ljung R et al. Br. J. Haematol. 2015 Mar 29.

Optimal treatment strategies for hemophilia: achievements and limitations of current prophylactic regimens.
Oldenburg J et al. Blood 2015 Mar 26. (13) 2038-2044

FVIII inhibitors: pathogenesis and avoidance.
Astermark Jan et al. Blood 2015 Feb 23.

Rare bleeding disorders: diagnosis and treatment.
Palla Roberta et al. Blood 2015 Feb 23.

Haemophilia A: Pharmacoeconomic review of prophylaxis treatment versus on-demand.
Unim Brigid et al. ScientificWorldJournal 2015;2015:596164.

Hemophilia A: Dental considerations and management.
Shastry Shilpa Padar et al. J Int Soc Prev Community Dent 2014 Dec (Suppl 3) S147-52

Prophylaxis with FEIBA in paediatric patients with haemophilia A and inhibitors.
Ewing N et al. Haemophilia 2015 Jan 21.

Individualizing prophylaxis in hemophilia: a review.
Petrini Pia et al. Expert Rev Hematol 2015 Jan 20. 1-10

Hemophilia A: an ideal disease to correct in utero.
Porada Christopher D et al. Front Pharmacol 2014 276

Strategies for inhibitor treatment and costs in the short and long term: a critical evaluation of recent clinical studies.
Baghaipour Mohammad Reza et al. Eur. J. Haematol. 2015 Feb 30-7

Genetic risk factors for inhibitors in haemophilia A.
Bardi Edit et al. Eur. J. Haematol. 2015 Feb 7-10

Non-genetic risk factors and their influence on the management of patients in the clinic.
Álvarez Teresa et al. Eur. J. Haematol. 2015 Feb 2-6

Gene therapy for hemophilia.
Rogers Geoffrey L et al. Front Biosci (Landmark Ed) 2015 556-603

A new recombinant factor VIII: from genetics to clinical use.
Santagostino Elena et al. Drug Des Devel Ther 2014 2507-15

Hemophilia: Recent Insights and Progress in Gene Therapy - December 4, 2014

Nature Outlook Special Hemophilia Supplement (November, 2014)  Hopes are rising rapidly for people with the bleeding disorder haemophilia. The advent of longer-lasting blood-clotting factors is making treatment less onerous, and gene therapy offers a potential cure

Hemophilia video: Rockstars and flying cars

CDC information on hemophilia

Recent CDC articles:

Haemophilia Centre Accreditation Systems and Networks of Centres of Expertise for Rare Diseases in Europe and North America (off subscription)
Blood Transfusion 2014; 12 Suppl 3

The National Haemophilia program standards, evaluation and oversight systems in the United States of America.
Skinner MW, et al.  Blood Transfus 2014; 12 (Suppl 3): s542-8.

Prevalent inhibitors in haemophilia B subjects enrolled in the Universal Data Collection database
Puetz J, et al.  Haemophilia; 2014; Volume 20, Number 1, pp. 25-31

Identifying information needs among children and teens living with haemophilia
Simmons GM, et al.  Haemophilia; 2014; Volume 20, Number 1, pp. 1-8  

World Hemophilia Day: April 17 - April 17, 2014

CDC information: Hemophilia is an inherited bleeding disorder in which the blood does not clot properly

CDC information: Many people with hemophilia will develop an inhibitor

CDC information: Hemophilia and maintaining a healthy weight

CDC information: The safety of blood products is important for people with hemophilia

CDC information: Highlights from Surveillance- Report on the Universal Data Collection Program  [PDF 635.56 KB]