Cervical Cancer
Cervical Cancer: Screening and Genomic Insights - May 6, 2015
CDC and Related Info
- CDC Fact Sheet on Cervical Cancer
[PDF 873.72 KB]
- Human Papillomavirus (HPV) Information Portal
- Cervical cancer is preventable
- What should I know about screening?
- Genes reported in relation to cervical cancer, including genomewide association studies via theHuGE Navigator
Cervical cancer screening in average-risk women: Best practice advice from the Clinical Guidelines Committee of the American College of Physicians.
Sawaya GF et al. Ann. Intern. Med. 2015 Apr 30.
Sawaya GF et al. Ann. Intern. Med. 2015 Apr 30.
Cervical cancer screening in average-risk women.
Ann. Intern. Med. 2015 Apr 30.
Ann. Intern. Med. 2015 Apr 30.
Can genomic amplification of human telomerase gene and C-MYC in liquid-based cytological specimens be used as a method for opportunistic cervical cancer screening?
Gao K et al. Gynecol. Obstet. Invest. 2015 Apr 1.
Gao K et al. Gynecol. Obstet. Invest. 2015 Apr 1.
Quantitative DNA methylation analysis of candidate genes in cervical cancer.
Siegel EM et al. PLoS ONE 2015 (3) e0122495
Siegel EM et al. PLoS ONE 2015 (3) e0122495
Assessment of the association between micronuclei and the degree of uterine lesions and viral load in women with human papillomavirus.
Adam ML et al. Cancer Genomics Proteomics 2015 Mar-Apr (2) 67-71
Adam ML et al. Cancer Genomics Proteomics 2015 Mar-Apr (2) 67-71
Progression of naive intraepithelial neoplasia genome to aggressive squamous cell carcinoma genome of uterine cervix.
Jung Seung-Hyun et al. Oncotarget 2015 Feb 28. (6) 4385-93
Jung Seung-Hyun et al. Oncotarget 2015 Feb 28. (6) 4385-93
Global methylation silencing of clustered proto-cadherin genes in cervical cancer: serving as diagnostic markers comparable to HPV.
Wang Kai-Hung et al. Cancer Med 2015 Jan (1) 43-55
Wang Kai-Hung et al. Cancer Med 2015 Jan (1) 43-55
Human Papilloma Virus: Cervical Cancer and DNA Testing - January 23, 2015
CDC information: Human Papillomavirus (HPV) Information Portal
CDC Expert Commentary Podcast: Protect the Next Generation: Recommend the HPV Vaccine, Tom Frieden, CDC Director, August 18, 2014
Podcast: Protect the Next Generation: Recommend the HPV Vaccine, Tom Frieden, CDC Director, August 18, 2014
CDC information: Discover the link between HPV and Cancer
Recent Insights
Performance of self-collected cervical samples in screening for future precancer using human papillomavirus DNA testing.
Porras C, et al. J Natl Cancer Inst. 2014 Dec 5;107(1):400.
Porras C, et al. J Natl Cancer Inst. 2014 Dec 5;107(1):400.
Use of primary high-risk human papillomavirus testing for cervical cancer screening: Interim clinical guidance.
Huh WK, et al. Obstet Gynecol. 2015 Jan 7
Huh WK, et al. Obstet Gynecol. 2015 Jan 7
NCI paper: Cancer-associated infectious agents and epigenetic regulation.
Vedham V, Verma M. Methods Mol Biol. 2015;1238:333-54
Vedham V, Verma M. Methods Mol Biol. 2015;1238:333-54
TGFβ receptor 1: An immune susceptibility gene in HPV-associated cancer.
Levovitz C, et al. Cancer Res. 2014 Dec 1;74(23):6833-44
Levovitz C, et al. Cancer Res. 2014 Dec 1;74(23):6833-44
A comprehensive review of dysregulated miRNAs involved in cervical cancer.
Sharma G, et al. Curr Genomics. 2014 Aug;15(4):310-23
Sharma G, et al. Curr Genomics. 2014 Aug;15(4):310-23
Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism
Zheng Hu et al. Nature Genetics, January 12, 2015
Zheng Hu et al. Nature Genetics, January 12, 2015
Cervical Cancer: Insights from Genome-Wide Association Studies - January 26, 2015
Lessons and implications from association studies and post-GWAS analyses of cervical cancer.Chen D, Gyllensten U. Trends Genet. 2015 Jan;31(1):41-54.
Chen D, Gyllensten U. Trends Genet. 2015 Jan;31(1):41-54.
Pathway analysis of cervical cancer genome-wide association study highlights the MHC region and pathways involved in response to infection.
Chen D, et al. Hum Mol Genet. 2014 Nov 15;23(22):6047-60
Chen D, et al. Hum Mol Genet. 2014 Nov 15;23(22):6047-60
Genome-wide association study of susceptibility loci for cervical cancer.
Dan Chen, et al. JNCI (2013)
Dan Chen, et al. JNCI (2013)
Cervical Cancer: Genomics and Prevention - January 9, 2015
CDC information: January is Cervical Cancer Awareness Month - No woman should die of cervical cancer. The most important thing you can do to help prevent cervical cancer is to get screened regularly starting at age 21.
January is Cervical Health Awareness Month, Dana Sparks, Mayo Clinic, January 2015
Dana Sparks, Mayo Clinic, January 2015
Use of primary high-risk human papillomavirus testing for cervical cancer screening: Interim clinical guidance.
Huh WK, et al. Obstet Gynecol. 2015 Jan 7
Huh WK, et al. Obstet Gynecol. 2015 Jan 7
NCI paper: Cancer-associated infectious agents and epigenetic regulation.
Vedham V, Verma M. Methods Mol Biol. 2015;1238:333-54
Vedham V, Verma M. Methods Mol Biol. 2015;1238:333-54
TGFβ receptor 1: An immune susceptibility gene in HPV-associated cancer.
Levovitz C, et al. Cancer Res. 2014 Dec 1;74(23):6833-44
Levovitz C, et al. Cancer Res. 2014 Dec 1;74(23):6833-44
A comprehensive review of dysregulated miRNAs involved in cervical cancer.
Sharma G, et al. Curr Genomics. 2014 Aug;15(4):310-23
Sharma G, et al. Curr Genomics. 2014 Aug;15(4):310-23
Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism
Zheng Hu et al. Nature Genetics, January 12, 2015
Zheng Hu et al. Nature Genetics, January 12, 2015
Specialists split over HPV test's role in cancer screening, by Rob Stein, NPR, Jan 8
by Rob Stein, NPR, Jan 8Cervical Cancer: Genomics and Prevention - November 13, 2014
CDC Vital Signs: Cervical cancer is preventable, November 2014
Recent genomic insights
Clinical implications of (epi)genetic changes in HPV-induced cervical precancerous lesions.
Steenbergen RD, et al. Nat Rev Cancer. 2014 Jun;14(6):395-405.
Steenbergen RD, et al. Nat Rev Cancer. 2014 Jun;14(6):395-405.
Nucleic acid-based assays for the detection of high-risk human papillomavirus: a technical review.
Gibson JS. Cancer Cytopathol. 2014 Sep;122(9):639-45
Gibson JS. Cancer Cytopathol. 2014 Sep;122(9):639-45
Human papilloma virus, DNA methylation and microRNA expression in cervical cancer (Review).
Jiménez-Wences H, et al. Oncol Rep. 2014 Jun;31(6):2467-76.
Jiménez-Wences H, et al. Oncol Rep. 2014 Jun;31(6):2467-76.
Cervical Cancer Screening: Role of Genomic Testing - August 7, 2014
The US Food and Drug Administration approves 1st human papillomavirus DNA test for primary cervical cancer screening (April 24, 2014)
Alternative to pap test is approved by F.D.A., by Andrew Pollack, New York Times, Apr 24
(April 24, 2014)Alternative to pap test is approved by F.D.A.,
by Andrew Pollack, New York Times, Apr 24
Human papillomavirus testing for primary cervical cancer screening: Is it time to abandon Papanicolaou testing?
Sarah Feldman, JAMA Internal Medicine, July 28, 2014
Sarah Feldman, JAMA Internal Medicine, July 28, 2014
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