jueves, 9 de julio de 2015

Researchers Uncover How Flaviviruses Thwart the Body’s Antiviral Immunity

Researchers Uncover How Flaviviruses Thwart the Body’s Antiviral Immunity



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Wednesday July 08, 2015

How Do Viruses Evade Detection?

Cells infected by Langat virus

An NIAID-led international study uncovers how flaviviruses (tick-borne encephalitis virus, Langat virus, and likely West Nile virus) evade antiviral immune defenses by blocking a protein called prolidase.

The team also studied people with prolidase deficiency, a rare genetic disorder, and found impaired antiviral responses, likely accounting for some of the disease's symptoms. 

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